Name | 2-bromo-5-hydroxybenzaldehyde |
Synonyms | AKOS B020430 VHR CQ FE [WLN] ART-CHEM-BB B020430 4-BROMO-3-FORMYLPHENOL 2-bromo-5-hydroxybenzaldehyde 2-Bromo-5-hydroxybenzaldehyde 2-BROMO-5-HYDROXYBENZALDEHYDE Benzaldehyde, 2-bromo-5-hydroxy- 2-Bromo-5-(Hydroxyl)Benzaldehyde |
CAS | 2973-80-0 |
InChI | InChI=1/C7H5BrO2/c8-7-2-1-6(10)3-5(7)4-9/h1-4,10H |
InChIKey | SCRQAWQJSSKCFN-UHFFFAOYSA-N |
Molecular Formula | C7H5BrO2 |
Molar Mass | 201.02 |
Density | 1.737±0.06 g/cm3(Predicted) |
Melting Point | 130-135 °C |
Boling Point | 286.7±20.0 °C(Predicted) |
Flash Point | 127.2°C |
Solubility | Soluble in chloroform, dichloromethane and ethyl acetate. |
Vapor Presure | 0.00151mmHg at 25°C |
Appearance | Solid |
Color | White to Gray to Brown |
pKa | 8.67±0.18(Predicted) |
Storage Condition | Inert atmosphere,2-8°C |
Refractive Index | 1.657 |
MDL | MFCD03033065 |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R50 - Very Toxic to aquatic organisms R22 - Harmful if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 3077 |
WGK Germany | 3 |
Hazard Note | Irritant |
Hazard Class | 9 |
Packing Group | III |
Uses | 2-bromo-5-hydroxybenzaldehyde is used to prepare reactants of many drugs: Bcl-XL,PDE4 inhibitors, prostate cancer cell growth inhibitors and anti-inflammatory drugs. |
application | 2-bromo-5-hydroxybenzaldehyde is an intermediate in organic synthesis and a pharmaceutical intermediate, which can be used in laboratory research and development processes and chemical and pharmaceutical synthesis processes, and is mainly used as an intermediate in the Crisaborole of bulk drugs (AN2728). |